Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997582 | 0.81 | MAPK1 (0.36) | MAPK1NPSR1PKMGPR119KDM4C | |
| SCHEMBL27663425 | 0.73 | NPSR1 (0.33) | NPSR1ALDH1A1 | |
| SCHEMBL27763466 | 0.70 | MAPK1 (0.39) | MAPK1NPSR1PKMGPR119KDM4C | |
| SCHEMBL19031974 | 0.70 | ALOX5AP (0.41) | MAPK1NPSR1PKMGPR119KDM4C | |
| SCHEMBL21215959 | 0.70 | KDM4E (0.37) | MAPK1NPSR1PKMGPR119KDM4C | |
| SCHEMBL21216015 | 0.69 | MAPK1 (0.36) | MAPK1NPSR1PKMGPR119KDM4C | |
| SCHEMBL21197694 | 0.69 | MAPK1 (0.36) | MAPK1NPSR1PKMGPR119KDM4C | |
| SCHEMBL73421 | 0.69 | ALDH1A1 (0.41) | MAPK1NPSR1PKMGPR119KDM4C | |
| SCHEMBL3248705 | 0.68 | CYP3A4 (0.54) | ALDH1A1LMNASMN1; SMN2 | |
| Lithium Ion SCHEMBL21197693 | 0.68 | MAPK1 (0.35) | MAPK1NPSR1PKMGPR119KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105611923-A | Sodium channel modulators for the treatment of pain and diabetes | CHROMOCELL CORP | 2016-05-25 | — | — | CN | disclosed |