Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | FGB | P02675 | 1/20 | 0.34 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28075197 | 0.91 | KDM4E (0.45) | KDM4EKMT2ASMN1; SMN2CYP2D6L3MBTL1 | |
| Sulfuric Acid SCHEMBL28388331 | 0.91 | KDM4E (0.45) | KDM4EKMT2ASMN1; SMN2CYP2D6L3MBTL1 | |
| SCHEMBL1491038 | 0.87 | KDM4E (0.50) | KDM4EKMT2ASMN1; SMN2CYP2D6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28360520 | 0.86 | SMN1; SMN2 (0.49) | KDM4EKMT2ASMN1; SMN2CYP2D6L3MBTL1 | |
| Bromide SCHEMBL28228586 | 0.86 | KDM4E (0.49) | KDM4EKMT2ASMN1; SMN2CYP2D6L3MBTL1 | |
| Trifluoromethanesulfonic Acid SCHEMBL28615004 | 0.84 | KMT2A (0.45) | KDM4EKMT2ASMN1; SMN2CYP2D6L3MBTL1 | |
| SCHEMBL27778944 | 0.83 | KDM4E (0.44) | KDM4EKMT2ASMN1; SMN2CYP2D6L3MBTL1 | |
| SCHEMBL28851630 | 0.81 | KDM4E (0.45) | KDM4EKMT2ASMN1; SMN2CYP2D6L3MBTL1 | |
| SCHEMBL28276824 | 0.81 | KDM4E (0.45) | KDM4EKMT2ASMN1; SMN2CYP2D6L3MBTL1 | |
| Nitric Acid SCHEMBL28058756 | 0.79 | KDM4E (0.43) | KDM4EKMT2ASMN1; SMN2CYP2D6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104591938-B | Synthetic method of pharmaceutical intermediate diarylmethane compound | HENAN POLYTECHNIC (CN) | 2016-05-25 | — | — | CN | disclosed |