Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | FGB | P02675 | 1/20 | 0.37 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491038 | 0.98 | KDM4E (0.50) | SMN1; SMN2KDM4EKMT2ACYP2D6FNTA | |
| Bromide SCHEMBL28228586 | 0.96 | KDM4E (0.49) | SMN1; SMN2KDM4EKMT2ACYP2D6FNTA | |
| Sulfuric Acid SCHEMBL28388331 | 0.91 | KDM4E (0.45) | SMN1; SMN2KDM4EKMT2ACYP2D6FNTA | |
| SCHEMBL28851630 | 0.91 | KDM4E (0.45) | SMN1; SMN2KDM4EKMT2ACYP2D6FNTA | |
| Sulfuric Acid SCHEMBL28075197 | 0.91 | KDM4E (0.45) | SMN1; SMN2KDM4EKMT2ACYP2D6FNTA | |
| SCHEMBL28276824 | 0.91 | KDM4E (0.45) | SMN1; SMN2KDM4EKMT2ACYP2D6FNTA | |
| Nitric Acid SCHEMBL28058756 | 0.89 | KDM4E (0.43) | SMN1; SMN2KDM4EKMT2ACYP2D6FNTA | |
| SCHEMBL28075196 | 0.86 | KDM4E (0.41) | SMN1; SMN2KDM4EKMT2ACYP2D6FNTA | |
| Trifluoromethanesulfonic Acid SCHEMBL28615004 | 0.85 | KMT2A (0.45) | SMN1; SMN2KDM4EKMT2ACYP2D6FNTA | |
| SCHEMBL3087031 | 0.81 | KMT2A (0.43) | SMN1; SMN2KDM4EKMT2ACYP2D6FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119157785-A | Preparation method of modified ganoderma lucidum extract with whitening effect | 浙江慧和健康科技有限公司 | 2024-12-20 | — | — | CN | claimed |
| CN-118491248-B | Method for treating tail gas of continuous condensation section of RT (reverse transcription) pessary | 江苏环保产业技术研究院股份公司 | 2024-10-18 | — | — | CN | claimed |
| CN-118530451-A | Method for preparing self-repairing polyamide type ionic gel based on Ugi multicomponent polymerization reaction | 平顶山神马工程塑料科技发展有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-118491248-A | Method for treating tail gas of continuous condensation section of RT (reverse transcription) pessary | 江苏环保产业技术研究院股份公司 | 2024-08-16 | — | — | CN | claimed |
| CN-116903558-A | Method for extracting paclitaxel from Taxus genus plant | 北京理工大学 | 2023-10-20 | — | — | CN | claimed |
| CN-116770581-B | Method for preparing antioxidant carbon fiber solid felt by adopting metal ion purifying agent | 烟台奥森制动材料有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-116770581-A | Method for preparing antioxidant carbon fiber solid felt by adopting metal ion purifying agent | 烟台奥森制动材料有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-114762736-A | Ionic liquid modified chitosan hydrogel and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所慈溪生物医学工程研究所 | 2022-07-19 | — | — | CN | claimed |
| CN-112680277-B | Method for preparing sulfurized fatty acid by using kitchen waste oil and method for preparing lubricating oil | 正大国际科技(常德)集团有限公司 | 2022-06-03 | — | — | CN | claimed |
| CN-112625803-B | Preparation method of environment-friendly bio-based lubricating grease | 正大国际科技(常德)集团有限公司 | 2022-06-03 | — | — | CN | claimed |
| CN-110451454-B | Cross-scale friction-reducing wear-resisting modification method and characterization method for monocrystalline silicon surface | 湘潭大学 | 2022-04-22 | — | — | CN | claimed |
| CN-111943203-B | Preparation method and application of vacancy manganese-based MAX | 郑州轻工业大学 | 2021-09-24 | — | — | CN | claimed |
| CN-113201183-A | Anti-blocking functional master batch with antistatic effect and preparation method and application thereof | 安徽国风塑业股份有限公司 | 2021-08-03 | — | — | CN | claimed |
| CN-110841718-B | Method for packaging heteropoly acid ionic liquid through Zr-based MOFs in-situ bridging | 福州大学 | 2021-07-13 | — | — | CN | claimed |
| CN-112680277-A | Method for preparing sulfurized fatty acid by using kitchen waste oil | 正大国际科技(常德)集团有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-112625803-A | Method for preparing higher fatty acid ester by using illegal cooking oil | 正大国际科技(常德)集团有限公司 | 2021-04-09 | — | — | CN | claimed |
| CN-111943203-A | Preparation method and application of vacancy manganese-based MAX | 郑州轻工业大学 | 2020-11-17 | — | — | CN | claimed |
| CN-108525655-B | Preparation method and application of novel composite catalyst for oxidizing hydroxyl into carbonyl | 扬州工业职业技术学院 | 2020-07-24 | — | — | CN | claimed |
| CN-108335917-B | Preparation method of carbon nanofiber loaded orderly-arranged reduced graphene oxide electrode material | 渤海大学 | 2020-04-21 | — | — | CN | claimed |
| CN-110841718-A | Method for packaging heteropoly acid ionic liquid through Zr-based MOFs in-situ bridging | 福州大学 | 2020-02-28 | — | — | CN | claimed |