Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PPOX | P50336 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27343161 | 0.82 | TDP1 (0.65) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL11056890 | 0.81 | TDP1 (0.53) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL8505688 | 0.81 | KMT2A (0.45) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL11303611 | 0.79 | TDP1 (0.48) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10853274 | 0.78 | EPAS1 (0.55) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL28073333 | 0.77 | KMT2A (0.48) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL28259258 | 0.77 | EPAS1 (0.54) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL8772383 | 0.76 | EPAS1 (0.49) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL11498163 | 0.76 | EPAS1 (0.51) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL11922554 | 0.75 | TDP1 (0.59) | TDP1MEN1TTRPPOXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105601519-A | Preparation method of acifluorfen | BEIJING YINGTAIJIAHE BIOTECHNOLOGY CO LTD | 2016-05-25 | — | — | CN | disclosed |