Thiourea

Thiourea

SCHEMBL28075286

CC(C)=NNC(N)=O.NC(N)=S

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.44
LMNA P02545 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
TAS2R38 P59533 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CRBN Q96SW2 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
HIF1A Q16665 1/20 0.36
CTH P32929 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6219184 0.92
Urea SCHEMBL28239709 0.90 ALDH1A1 (0.47) ALDH1A1LMNASMN1; SMN2CYP1A2CYP2C9
Hydrogen Sulfide SCHEMBL27650023 0.90
Urea SCHEMBL28172761 0.87 ALDH1A1 (0.45) ALDH1A1LMNASMN1; SMN2CYP1A2CYP2C9
SCHEMBL12121703 0.76
SCHEMBL15131361 0.76 ALDH1A1 (0.48) ALDH1A1LMNASMN1; SMN2CYP1A2CYP2C9
SCHEMBL233447 0.76
SCHEMBL27763205 0.74 CRBN (0.38) ALDH1A1LMNASMN1; SMN2CYP1A2CYP2C9
SCHEMBL15131400 0.72 ALDH1A1 (0.45) ALDH1A1LMNASMN1; SMN2CYP1A2CYP2C9
SCHEMBL1639601 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106565872-A Preparation method of CPVC resin by water-phase suspension method 中国石油化工股份有限公司 2017-04-19 CN claimed
CN-106543056-A The preparation method of acetone semicarbazone thiourea and its obtained acetone semicarbazone thiourea 宁夏顺邦达化工有限公司 2017-03-29 CN claimed
CN-104356272-B The micro-suspension polymerization of styrene-N-phenylmaleimide-acrylonitrile SICHUAN ZHIJIANG ADVANCED MATERIALS CO., LTD. (CN) 2017-01-04 CN claimed
CN-106008772-A Method for safely controlling polymerization reaction of vinyl acetate-methanol mixed liquid 中国石油化工股份有限公司 2016-10-12 CN claimed
CN-105801728-A PVC resin oil-soluble terminator and preparation method thereof 乌鲁木齐市华泰隆化学助剂有限公司 2016-07-27 CN claimed
CN-105732857-A Composite polyvinyl chloride resin oil-soluble terminator and preparation method thereof 乌鲁木齐市华泰隆化学助剂有限公司 2016-07-06 CN claimed
CN-106565872-A Preparation method of CPVC resin by water-phase suspension method 中国石油化工股份有限公司 2017-04-19 CN disclosed
CN-106543056-A The preparation method of acetone semicarbazone thiourea and its obtained acetone semicarbazone thiourea 宁夏顺邦达化工有限公司 2017-03-29 CN disclosed
CN-106543056-A The preparation method of acetone semicarbazone thiourea and its obtained acetone semicarbazone thiourea 宁夏顺邦达化工有限公司 2017-03-29 CN disclosed
CN-106543056-A The preparation method of acetone semicarbazone thiourea and its obtained acetone semicarbazone thiourea 宁夏顺邦达化工有限公司 2017-03-29 CN disclosed
CN-103018082-B Heavy metal collection method and heavy metal recovery reagent used in it 爱科来株式会社 2017-03-01 CN disclosed
CN-104356272-B The micro-suspension polymerization of styrene-N-phenylmaleimide-acrylonitrile SICHUAN ZHIJIANG ADVANCED MATERIALS CO., LTD. (CN) 2017-01-04 CN disclosed
CN-106008772-A Method for safely controlling polymerization reaction of vinyl acetate-methanol mixed liquid 中国石油化工股份有限公司 2016-10-12 CN disclosed
CN-104603195-B Oxygen-absorbing resin composition and the oxygen uptake polylayer forest using it 三菱瓦斯化学株式会社 2016-09-21 CN disclosed
CN-105801728-A PVC resin oil-soluble terminator and preparation method thereof 乌鲁木齐市华泰隆化学助剂有限公司 2016-07-27 CN disclosed
CN-105732857-A Composite polyvinyl chloride resin oil-soluble terminator and preparation method thereof 乌鲁木齐市华泰隆化学助剂有限公司 2016-07-06 CN disclosed