SCHEMBL28075403

SCHEMBL28075403

O=S(=O)(Oc1ccccc1)c1ccccc1.[NaH].[NaH]

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.70
CA2 P00918 4/20 0.54
CA1 P00915 2/20 0.54
CA9 Q16790 2/20 0.54
MAPT P10636 4/20 0.53
ALDH1A1 P00352 4/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
MAOB P27338 1/20 0.53
CA12 O43570 2/20 0.49
PARL Q9H300 1/20 0.48
ENPP3 O14638 4/20 0.47
ENPP1 P22413 4/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
HPGD P15428 1/20 0.47
ENPP2 Q13822 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7981247 0.98 TDP1 (0.73) TDP1CA2CA1CA9MAPT
SCHEMBL19146 0.98 TDP1 (0.73) TDP1CA2CA1CA9MAPT
SCHEMBL28157244 0.95 TDP1 (0.70) TDP1CA2CA1CA9MAPT
SCHEMBL1674227 0.95 TDP1 (0.70) TDP1CA2CA1CA9MAPT
Ammonia Solution, Strong SCHEMBL28247173 0.95 TDP1 (0.70) TDP1CA2CA1CA9MAPT
SCHEMBL28934632 0.95 TDP1 (0.70) TDP1CA2CA1CA9MAPT
Benzene SCHEMBL27543065 0.95 TDP1 (0.70) TDP1CA2CA1CA9MAPT
SCHEMBL28184027 0.95 TDP1 (0.70) TDP1CA2CA1CA9MAPT
Ammonia Solution, Strong SCHEMBL8363523 0.95 TDP1 (0.70) TDP1CA2CA1CA9MAPT
Formaldehyde SCHEMBL9220828 0.93 TDP1 (0.68) TDP1CA2CA1CA9MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110527013-A A kind of preparation method of the double cross-linked acrylate rubbers of hardy type JIUJIANG DOWELL RUBBER TECH CO LTD 2019-12-03 CN disclosed
CN-105682749-A Alkali-swellable crosslinked acrylate copolymer, methods of manufacture thereof, and composition comprising the same 联合碳化化学品及塑料技术有限责任公司 2016-06-15 CN disclosed
CN-104640890-A A multi-stage polymer as a grinding additive and preparation process thereof ROHM & HAAS 2015-05-20 CN disclosed
CN-103890132-A Surfactant responsive microgels LUBRIZOL ADVANCED MAT INC 2014-06-25 CN disclosed
CN-103890131-A SURFACTANT RESPONSIVE MICRO-GELS LUBRIZOL ADVANCED MAT INC 2014-06-25 CN disclosed