SCHEMBL28075448

SCHEMBL28075448

O=C(/C=C/c1ccccc1)c1ccc2cccc(O)c2n1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.60
KDM4E B2RXH2 3/20 0.60
PIM1 P11309 1/20 0.55
MAPT P10636 4/20 0.53
BCHE P06276 2/20 0.53
CYP2C19 P33261 1/20 0.53
ABCG2 Q9UNQ0 2/20 0.52
RAB9A P51151 3/20 0.51
NPC1 O15118 2/20 0.51
MEN1 O00255 2/20 0.51
POLB P06746 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
CYP1B1 Q16678 5/20 0.50
LMNA P02545 2/20 0.50
PKM P14618 2/20 0.50
MAOB P27338 2/20 0.50
PLIN1 O60240 1/20 0.50
TNFRSF1A P19438 1/20 0.50
ACHE P22303 1/20 0.50
RECQL P46063 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28075449 1.00 KMT2A (0.60) KMT2AKDM4EPIM1MAPTBCHE
SCHEMBL437765 0.99 KMT2A (0.59) KMT2AKDM4EPIM1MAPTBCHE
SCHEMBL28095215 0.99 KMT2A (0.59) KMT2AKDM4EPIM1MAPTBCHE
SCHEMBL6283674 0.99 KMT2A (0.59) KMT2AKDM4EPIM1MAPTBCHE
SCHEMBL10275159 0.89 KMT2A (0.54) KMT2AKDM4EPIM1MAPTABCG2
SCHEMBL10275201 0.88 MAPT (0.55) KMT2AKDM4EPIM1MAPTCYP2C19
SCHEMBL10275586 0.85 USP2 (0.60) KMT2AKDM4EPIM1MAPTRAB9A
Zinc Ion SCHEMBL1462515 0.83 MAPT (0.48) KMT2AKDM4EMAPTBCHECYP2C19
Zinc Ion SCHEMBL1462511 0.83 MAPT (0.48) KMT2AKDM4EMAPTBCHECYP2C19
SCHEMBL27625905 0.80 LMNA (0.51) KMT2AKDM4EMAPTBCHEABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101634725-B Blue coloring composition for color filter, color filter and colour display device 东洋油墨制造株式会社 2016-10-05 CN disclosed
CN-102255050-B Light-emitting component, luminescent device, electronic device and illuminating device 株式会社半导体能源研究所 2016-08-10 CN disclosed
CN-105742516-A Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device 株式会社半导体能源研究所 2016-07-06 CN disclosed