Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | ERN1 | O75460 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2618846 | 0.83 | MEN1 (0.54) | HTTKMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL34473937 | 0.82 | MEN1 (0.72) | HTTKMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6747694 | 0.82 | MEN1 (0.72) | HTTKMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL13071682 | 0.80 | ERN1 (0.52) | HTTKMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL18688897 | 0.76 | SMN1; SMN2 (0.68) | HTTKMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7933060 | 0.71 | HTT (0.66) | HTTKMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL13278283 | 0.71 | HTT (0.66) | HTTKMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3236587 | 0.71 | MEN1 (1.00) | HTTKMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL5162979 | 0.71 | HTT (0.66) | HTTKMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3353163 | 0.70 | ERN1 (0.44) | HTTKMT2AMEN1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103641765-B | ATP-combines the adjusting control agent of cassette transporters | 沃泰克斯药物股份有限公司 | 2016-08-17 | — | — | CN | disclosed |