Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | GALR3 | O60755 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161208 | 0.89 | HTT (0.58) | HTTSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL21653949 | 0.89 | ALDH1A1 (0.58) | HTTSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL12824753 | 0.87 | HTT (0.56) | HTTSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL12825156 | 0.83 | XDH (0.60) | HTTSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL698724 | 0.83 | HTT (0.56) | HTTSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL31125147 | 0.80 | ALDH1A1 (0.58) | HTTSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL3523467 | 0.80 | ALDH1A1 (0.58) | HTTSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL3236587 | 0.79 | MEN1 (1.00) | HTTSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL7933060 | 0.79 | HTT (0.66) | HTTSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL11677753 | 0.79 | ALDH1A1 (0.50) | HTTSMN1; SMN2MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864343-B | Binuclear (alpha-diimine) nickel/palladium olefin catalyst, preparation and application | 浙江大学 | 2021-01-05 | — | — | CN | disclosed |
| CN-108864342-B | Binuclear (alpha-diimine) nickel/palladium olefin catalyst and preparation and application thereof | 浙江大学 | 2020-10-09 | — | — | CN | disclosed |
| EP-1757579-A1 | Primary 2,6-disubstituted para-phenylenediamines and their uses for dyeing keratin fibres | L'Oréal (FR) | 2007-02-28 | — | — | EP | disclosed |