Trolamine

Trolamine

SCHEMBL28075795

CCCCCN(C)C(C)C(=O)O.OCCN(CCO)CCO

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ICMT O60725 2/20 0.36
ALB P02768 2/20 0.36
KDM5A P29375 5/20 0.36
PHF8 Q9UPP1 3/20 0.36
KDM4C Q9H3R0 3/20 0.36
ACE2 Q9BYF1 1/20 0.35
GPR84 Q9NQS5 3/20 0.34
FFAR1 O14842 1/20 0.34
CNR1 P21554 1/20 0.34
MMP1 P03956 1/20 0.34
MMP3 P08254 1/20 0.34
MAPT P10636 1/20 0.33
KDM5C P41229 1/20 0.33
KDM5B Q9UGL1 1/20 0.33
LCK P06239 1/20 0.33
PPARD Q03181 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
GGPS1 O95749 3/20 0.33
DNM1 Q05193 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL7262076 0.98 ICMT (0.38) ICMTALBKDM5APHF8KDM4C
Trolamine SCHEMBL28007192 0.98 ICMT (0.38) ICMTALBKDM5APHF8KDM4C
SCHEMBL16967370 0.89 ACE2 (0.41) KDM5APHF8KDM4CACE2GPR84
SCHEMBL3878796 0.89 ACE2 (0.41) KDM5APHF8KDM4CACE2GPR84
SCHEMBL2846897 0.89 ACE2 (0.41) KDM5APHF8KDM4CACE2GPR84
SCHEMBL5495146 0.88 ACE2 (0.44) ACE2GPR84FFAR1MMP1MMP3
SCHEMBL2175914 0.88 ACE2 (0.44) ACE2GPR84FFAR1MMP1MMP3
SCHEMBL7497648 0.88 ACE2 (0.44) ACE2GPR84FFAR1MMP1MMP3
SCHEMBL7500724 0.88 ACE2 (0.44) ACE2GPR84FFAR1MMP1MMP3
SCHEMBL7500730 0.88 ACE2 (0.44) ACE2GPR84FFAR1MMP1MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105997546-A Body cleansing composition 日油株式会社 2016-10-12 CN disclosed
CN-105848626-A Transparent composition containing oil and microcapsules 莱雅公司 2016-08-10 CN disclosed