⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164614 | 0.65 | — | — | |
| SCHEMBL16756622 | 0.56 | — | — | |
| SCHEMBL3860968 | 0.56 | — | — | |
| SCHEMBL11777775 | 0.56 | — | — | |
| SCHEMBL28091458 | 0.56 | ALDH1A1 (0.33) | — | |
| SCHEMBL1961807 | 0.56 | — | — | |
| SCHEMBL12919196 | 0.56 | — | — | |
| SCHEMBL2142832 | 0.56 | — | — | |
| SCHEMBL6884238 | 0.54 | ALDH1A1 (0.35) | — | |
| SCHEMBL1137963 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641910-A | Pyrroles acene phenodiazine * and its conjugate | 梅尔莎纳医疗公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-109310885-A | NaPi2b targeting antibodies-drug conjugate and its application method | 梅尔莎纳医疗公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-106110332-B | Protein-polymer-drug conjugate | 梅尔莎纳医疗公司 | 2018-11-30 | — | — | CN | disclosed |
| CN-108884146-A | Factor IX with extended half-life period and reduced ligand binding property | 百深公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-106110332-A | Protein polymer drug conjugate | 梅尔莎纳医疗公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-103747804-B | protein-polymer-drug conjugates | 梅尔莎纳医疗公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-105813655-A | Protein-polymer-drug conjugates | 阿萨纳生物科技有限责任公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-103747804-A | Protein-polymer-drug conjugates | MERSANA THERAPEUTICS INC | 2014-04-23 | — | — | CN | disclosed |