Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL27411671 | 0.87 | ALDH1A1 (0.33) | LMNA | |
| SCHEMBL858254 | 0.87 | — | — | |
| Phosphine SCHEMBL28160341 | 0.85 | — | — | |
| Methane SCHEMBL28208466 | 0.85 | — | — | |
| SCHEMBL28034541 | 0.85 | — | — | |
| Hydrogen Sulfide SCHEMBL27864758 | 0.85 | — | — | |
| SCHEMBL28582167 | 0.85 | — | — | |
| SCHEMBL28303446 | 0.85 | — | — | |
| Formaldehyde SCHEMBL27688351 | 0.82 | — | — | |
| Acetic Acid SCHEMBL28021602 | 0.81 | FFAR3 (0.33) | FFAR3LCKFYNLMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108495820-A | Polyoxometallates comprising noble metals and corresponding metal clusters | 埃克森美孚化学专利公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-103540614-B | The signal of packaging of influenza virus vectors | 威斯康星旧生研究基金会 | 2018-02-02 | — | — | CN | disclosed |
| CN-103875117-B | Non-aqueous electrolyte and lithium secondary battery containing phosphono sulfoacid compound | 三井化学株式会社 | 2016-08-17 | — | — | CN | disclosed |