Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27532994 | 0.79 | ENPP2 (0.59) | ENPP2CA2CA9CA12CA3 | |
| SCHEMBL21133795 | 0.79 | ENPP2 (0.59) | ENPP2CA2CA9CA12CA3 | |
| SCHEMBL1820855 | 0.77 | ENPP2 (0.65) | ENPP2ALDH1A1TSHRMAPTGSK3B | |
| SCHEMBL23797214 | 0.76 | ENPP2 (0.55) | ENPP2CA2CA9CA12CA3 | |
| SCHEMBL2405727 | 0.75 | ENPP2 (0.73) | ENPP2CA2CA9CA12CA3 | |
| SCHEMBL6016 | 0.75 | ENPP2 (1.00) | ENPP2CA2CA9CA12CA3 | |
| SCHEMBL20975981 | 0.75 | ENPP2 (0.53) | ENPP2CA2CA9CA12CA3 | |
| SCHEMBL14421551 | 0.74 | ENPP2 (0.64) | ENPP2CA2CA9CA12CA3 | |
| SCHEMBL1138376 | 0.73 | ENPP2 (0.52) | ENPP2CA2CA9CA12CA3 | |
| SCHEMBL21336582 | 0.71 | ENPP2 (0.67) | ENPP2CA2CA9CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106488921-B | Aldosterone synthase inhibitors | 勃林格殷格翰国际有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-107406433-A | Derivatives of 2, 3-diphenylchromene for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-103958487-B | Benzoic acid derivative as EIF4E inhibitor | 霍夫曼-拉罗奇有限公司 | 2016-07-13 | — | — | CN | disclosed |