Methane

Methane

SCHEMBL28075995

C.O=C(c1ccccc1)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
CTSD P07339 1/20 0.54
VCAM1 P19320 1/20 0.53
MAPK1 P28482 1/20 0.53
GAA P10253 2/20 0.52
MAPT P10636 2/20 0.52
HTT P42858 1/20 0.52
KDM4E B2RXH2 1/20 0.52
HPGD P15428 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
AKR1C3 P42330 1/20 0.52
TSHR P16473 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
CDC25B P30305 1/20 0.49
POLB P06746 1/20 0.49
MAOB P27338 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL411359 0.98 ALDH1A1 (0.59) ALDH1A1CTSDVCAM1MAPK1GAA
SCHEMBL27637513 0.98 ALDH1A1 (0.59) ALDH1A1CTSDVCAM1MAPK1GAA
SCHEMBL28783981 0.96 ALDH1A1 (0.58) ALDH1A1CTSDVCAM1MAPK1GAA
Benzene SCHEMBL28261609 0.96 ALDH1A1 (0.58) ALDH1A1CTSDVCAM1MAPK1GAA
Water SCHEMBL28136320 0.96 ALDH1A1 (0.58) ALDH1A1CTSDVCAM1MAPK1GAA
Water SCHEMBL4951772 0.96 ALDH1A1 (0.58) ALDH1A1CTSDVCAM1MAPK1GAA
Hydrogen Sulfide SCHEMBL28794532 0.96 ALDH1A1 (0.58) ALDH1A1CTSDVCAM1MAPK1GAA
SCHEMBL28110765 0.96 ALDH1A1 (0.58) ALDH1A1CTSDVCAM1MAPK1GAA
Bicarbonate SCHEMBL27635106 0.96 ALDH1A1 (0.58) ALDH1A1CTSDVCAM1MAPK1GAA
Benzophenone SCHEMBL27809239 0.96 ALDH1A1 (0.58) ALDH1A1CTSDVCAM1MAPK1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104177788-B Hydrolysis-resistant aliphatic polyester resin composition and preparation method thereof 中国科学院理化技术研究所 2017-11-21 CN claimed
CN-110167355-A MULTI-DRUG ANTIBODY DRUG CONJUGATES 西雅图基因公司 2019-08-23 CN disclosed
CN-109890417-A The treatment of cancer and/or prophylactic compositions 东丽株式会社 2019-06-14 CN disclosed
CN-109104862-A 4, 9-dioxo-4, 9-dihydronaphtho [2,3-b ] furan-3-carboxamide derivatives and their use for the treatment of proliferative and infectious diseases 中央研究院 2018-12-28 CN disclosed
CN-101420977-B Nogo receptor antagonists 比奥根MA公司 2016-08-10 CN disclosed