SCHEMBL28076067

SCHEMBL28076067

C=CCc1cc2ccccc2o1.[SiH4]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.56
AGXT P21549 1/20 0.51
HTR2B P41595 4/20 0.44
HTR1A P08908 2/20 0.44
CYP2A6 P11509 2/20 0.43
CYP19A1 P11511 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ADRA2A P08913 1/20 0.41
KDM4E B2RXH2 2/20 0.40
DRD2 P14416 2/20 0.40
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
NFKB1 P19838 1/20 0.40
RAB9A P51151 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
ESR1 P03372 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL859678 0.98 LOXL2 (0.58) LOXL2AGXTHTR2BHTR1ACYP2A6
SCHEMBL30511855 0.98 LOXL2 (0.58) LOXL2AGXTHTR2BHTR1ACYP2A6
SCHEMBL28768145 0.79 LOXL2 (0.58) LOXL2AGXTHTR2BHTR1ACYP2A6
SCHEMBL112634 0.79 LOXL2 (0.58) LOXL2AGXTHTR2BHTR1ACYP2A6
SCHEMBL1776301 0.79 LOXL2 (0.58) LOXL2AGXTHTR2BHTR1ACYP2A6
SCHEMBL3264177 0.76 LOXL2 (0.59) LOXL2AGXTHTR2BHTR1ACYP2A6
SCHEMBL5793787 0.76 LOXL2 (0.55) LOXL2AGXTHTR2BHTR1ACYP2A6
SCHEMBL28311732 0.76 LOXL2 (0.55) LOXL2AGXTHTR2BHTR1ACYP2A6
SCHEMBL4386951 0.76 LOXL2 (0.55) LOXL2AGXTHTR2BHTR1ACYP2A6
SCHEMBL291730 0.76 LOXL2 (0.64) LOXL2AGXTHTR2BHTR1ACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103517906-B 4H-imidazo [1,2-a ] imidazoles for electronic applications 巴斯夫欧洲公司 2016-08-24 CN disclosed