SCHEMBL28076165

SCHEMBL28076165

CC(=O)NOc1ccc(Cl)cc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.51
TSHR P16473 2/20 0.51
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
MAPT P10636 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
HPGD P15428 5/20 0.46
USP2 O75604 1/20 0.45
SLC6A2 P23975 2/20 0.45
SLC6A3 Q01959 2/20 0.45
SLC6A4 P31645 1/20 0.45
TTR P02766 2/20 0.44
NR1I2 O75469 1/20 0.44
LMNA P02545 1/20 0.44
PGR P06401 1/20 0.44
HSP90AA1 P07900 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
HSPA5 P11021 1/20 0.44
CBR1 P16152 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrimidine SCHEMBL27709524 0.88 LMNA (0.46) TDP1TSHRKMT2AMEN1MAPT
SCHEMBL27351068 0.83 NPC1 (0.44) KMT2AMEN1L3MBTL1SMN1; SMN2HPGD
Acetic Acid SCHEMBL28188378 0.82 TDP1 (0.49) TDP1TSHRKMT2AMEN1MAPT
SCHEMBL27816666 0.81 TSHR (0.52) TDP1TSHRKMT2AMEN1MAPT
SCHEMBL11165570 0.81 MEN1 (0.47) TDP1TSHRKMT2AMEN1MAPT
SCHEMBL6790962 0.81 TDP1 (0.47) TDP1TSHRKMT2AMEN1MAPT
SCHEMBL30801345 0.80 ABL1 (0.55) TDP1KMT2AMEN1MAPTSMN1; SMN2
SCHEMBL7397469 0.80 ABL1 (0.55) TDP1KMT2AMEN1MAPTSMN1; SMN2
SCHEMBL21676840 0.80 TDP1 (0.50) TDP1TSHRKMT2AMEN1MAPT
SCHEMBL18011815 0.80 TSHR (0.43) TDP1TSHRKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104140493-B A kind of water-soluble ionic-type hydrophobic associated polymer oil displacement agent and its preparation method and application 西南石油大学 2016-08-17 CN disclosed