Methacrylic Acid

Methacrylic Acid

SCHEMBL28076204

C=C(C)C(=O)O.C=C(C)C(=O)OCCN(C)C.C=CC(=O)OCCN(C)C

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.41
HPGD P15428 1/20 0.41
ALDH1A1 P00352 4/20 0.41
TP53 P04637 2/20 0.41
HIF1A Q16665 2/20 0.41
CYP3A4 P08684 1/20 0.41
HSD17B10 Q99714 1/20 0.41
THRB P10828 3/20 0.40
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRNB2 P17787 1/20 0.40
CHRM3 P20309 1/20 0.40
CHRNA4 P43681 1/20 0.40
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
DNM1 Q05193 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1538397 0.95 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL4594665 0.94 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
Acrylic Acid Ethyl Ester SCHEMBL7542173 0.93 THRB (0.44) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL28158608 0.91 THRB (0.42) TSHRALDH1A1HSD17B10THRBCHRM2
Methacrylic Acid SCHEMBL28018497 0.91 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28123718 0.90 TSHR (0.56) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9506277 0.90 TSHR (0.56) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL319586 0.89 THRB (0.48) TSHRALDH1A1THRBCHRM2CHRM4
Methacrylic Acid SCHEMBL11969913 0.89 THRB (0.48) TSHRALDH1A1THRBCHRM2CHRM4
Acrylic Acid Ethyl Ester SCHEMBL239185 0.88 THRB (0.47) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105739237-A PHOTOLITHOGRAPHIC METHODS 罗门哈斯电子材料有限责任公司 2016-07-06 CN disclosed