SCHEMBL28076475

SCHEMBL28076475

C=CC=COC(=O)CC(C)=O

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.44
GAA P10253 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7117226 0.78 MGAM (0.48) MGAMGAASIMGAM2
SCHEMBL5177210 0.78
SCHEMBL5177208 0.78
SCHEMBL19746063 0.78 TSHR (0.32)
SCHEMBL19746061 0.78 TSHR (0.32)
SCHEMBL94026 0.78
SCHEMBL19746156 0.76
SCHEMBL19746162 0.76
SCHEMBL28268379 0.76 ALOX15 (0.44)
SCHEMBL28766415 0.76 MGAM (0.50) MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104529868-B 2,3-disubstituted indole oxazoline derivates and preparation method thereof 中国农业大学 2016-08-17 CN claimed
CN-115466177-A Method for preparing 1, 4-diacetyloxy-2-butene 中国科学院大连化学物理研究所 2022-12-13 CN disclosed
CN-115466177-A Method for preparing 1, 4-diacetyloxy-2-butene 中国科学院大连化学物理研究所 2022-12-13 CN disclosed
CN-107954873-A A kind of polysubstituted olefin(e) acid ester derivant and preparation method thereof 安徽师范大学 2018-04-24 CN disclosed
CN-104529868-B 2,3-disubstituted indole oxazoline derivates and preparation method thereof 中国农业大学 2016-08-17 CN disclosed