Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 2/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867116 | 0.95 | HDAC6 (0.68) | HDAC6HDAC2HDAC8HDAC1HPGD | |
| SCHEMBL11900090 | 0.88 | HDAC6 (0.85) | HDAC6HDAC2HDAC8HDAC1HPGD | |
| SCHEMBL16058342 | 0.86 | HDAC6 (0.72) | HDAC6HDAC2HDAC8HDAC1HPGD | |
| SCHEMBL22987225 | 0.85 | PPARG (0.81) | HDAC6HDAC2HDAC8HDAC1HPGD | |
| SCHEMBL27501943 | 0.85 | HDAC6 (0.66) | HDAC6HDAC2HDAC8HDAC1HPGD | |
| SCHEMBL13133467 | 0.85 | HDAC6 (0.66) | HDAC6HDAC2HDAC8HDAC1HPGD | |
| Hydrochloric Acid SCHEMBL2210739 | 0.84 | HDAC6 (0.64) | HDAC6HDAC2HDAC8HDAC1HPGD | |
| SCHEMBL457082 | 0.84 | HDAC6 (0.79) | HDAC6HDAC2HDAC8HDAC1HPGD | |
| SCHEMBL12338972 | 0.83 | HDAC3 (0.67) | HDAC6HDAC2HDAC8HDAC1LMNA | |
| SCHEMBL29151912 | 0.82 | HDAC6 (0.71) | HDAC6HDAC2HDAC8HDAC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658646-A | Aminoheteroaryl benzamides as kinase inhibitors | 诺华股份有限公司 | 2016-06-08 | — | — | CN | disclosed |