SCHEMBL457082

SCHEMBL457082

O=C(NCc1ccccc1)c1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 4/20 0.79
HDAC2 Q92769 2/20 0.79
HDAC8 Q9BY41 2/20 0.79
HDAC1 Q13547 2/20 0.76
HPGD P15428 1/20 0.73
TP53 P04637 1/20 0.72
LMNA P02545 1/20 0.71
RAB9A P51151 1/20 0.71
APOBEC3A P31941 1/20 0.69
CTDSP1 Q9GZU7 1/20 0.69
APOBEC3G Q9HC16 1/20 0.69
MITF O75030 1/20 0.68
ALDH1A1 P00352 1/20 0.68
ROCK2 O75116 1/20 0.67
RPS6KA5 O75582 1/20 0.67
MAP4K4 O95819 1/20 0.67
PRKCG P05129 1/20 0.67
PRKACA P17612 1/20 0.67
RPS6KB1 P23443 1/20 0.67
MAPK1 P28482 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3757721 0.98 HDAC6 (0.76) HDAC6HDAC2HDAC8HDAC1HPGD
SCHEMBL29184442 0.98 HDAC6 (0.76) HDAC6HDAC2HDAC8HDAC1HPGD
SCHEMBL11900090 0.96 HDAC6 (0.85) HDAC6HDAC2HDAC8HDAC1HPGD
SCHEMBL29151912 0.94 HDAC6 (0.71) HDAC6HDAC2HDAC8HDAC1HPGD
Alcohol SCHEMBL8615549 0.92 HDAC6 (0.69) HDAC6HDAC2HDAC8HDAC1HPGD
SCHEMBL22047184 0.91 PPARG (0.78) HDAC6HDAC2HDAC8HDAC1HPGD
Propionic Acid SCHEMBL28207638 0.91 HDAC6 (0.67) HDAC6HDAC2HDAC8HDAC1HPGD
SCHEMBL11901042 0.90 HDAC6 (0.70) HDAC6HDAC2HDAC8HDAC1HPGD
SCHEMBL6843720 0.90 HDAC6 (0.77) HDAC6HDAC2HDAC8HDAC1HPGD
SCHEMBL11900328 0.90 HDAC6 (0.87) HDAC6HDAC2HDAC8HDAC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 827 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4139286-B1 SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION BAYER AG (DE) 2025-02-26 EP claimed
CN-118994619-A Zirconium-based porous metal-organic framework catalyst, preparation method and application 东南大学 2024-11-22 CN claimed
CN-117700376-A N-benzyl benzamide compound, and pharmaceutical composition and application thereof 中国药科大学 2024-03-15 CN claimed
CN-109678815-B N-benzyl benzamide derivative and preparation method and pharmaceutical application thereof 中国药科大学 2022-11-29 CN claimed
CN-111187176-B Method for preparing N-vinyl amide compound under catalysis of copper salt 浙江工业大学 2022-11-25 CN claimed
US-20220330549-A1 USE OF N-BENZYLBENZAMIDE-BASED COMPOUND AS HERBICIDE NORTHWEST A&F UNIVERSITY (CN) 2022-10-20 US claimed
EP-3814359-B1 INHIBITORS OF GLUCOSE TRANSPORTERS (GLUTS) LEAD DISCOVERY CENTER GMBH (DE) 2022-08-17 EP claimed
CN-112203515-B Application of N-benzyl benzamide compound as herbicide 西北农林科技大学 2022-08-02 CN claimed
CN-114561093-A Low-viscosity polycaprolactone composite material 上海医妃医药科技有限公司 2022-05-31 CN claimed
CN-112203515-A Application of N-benzyl benzamide compound as herbicide 西北农林科技大学 2021-01-08 CN claimed
WO-1997016406-A1 PHOTOSENSITIVE INTRAMOLECULAR ELECTRON TRANSFER COMPOUNDS SPECTRA GROUP LIMITED, INC. (US) 1997-05-09 WO claimed
EP-0232716-B1 Polyphenylene ethers of improved stability GEN ELECTRIC (US) 1995-01-18 EP claimed
EP-0530286-B1 PROCESS FOR THE STEREOSELECTIVE PREPARATION OF PHENYLISOSERIN DERIVATIVES RHONE POULENC RORER SA (FR) 1994-08-03 EP claimed
US-5290957-A Process for the stereoselective preparation of phenylisoserine derivatives used in making taxols RHONE POULENC RORER S.A. (FR) 1994-03-01 US claimed
EP-0530286-A1 PROCESS FOR THE STEREOSELECTIVE PREPARATION OF PHENYLISOSERIN DERIVATIVES. RHONE POULENC RORER SA (FR) 1993-03-10 EP claimed
WO-1991017977-A1 PROCESS FOR THE STEREOSELECTIVE PREPARATION OF PHENYLISOSERIN DERIVATIVES RHONE-POULENC RORER S.A. (FR) 1991-11-28 WO claimed
EP-0349204-A2 Use and regeneration of reagents using coupled reactions and permselective barriers BEND RESEARCH, INC. (US) 1990-01-03 EP claimed
EP-0232716-A2 Polyphenylene ethers of improved stability GENERAL ELECTRIC COMPANY (US) 1987-08-19 EP claimed
US-4670537-A Polyphenylene ether containing amino-alkyl substituted end groups reacted with N--H compound GENERAL ELECTRIC COMPANY (US) 1987-06-02 US claimed
US-4358529-A BINDER, A HEXAARYLBIIMIDAZOLE, A DIHYDROPYRIDINE, AND AN IMIDOTHIOESTER OR A TAUTOMER; NONSILVER PHOTOGRAPHY E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-11-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220330549-A1 USE OF N-BENZYLBENZAMIDE-BASED COMPOUND AS HERBICIDE DDT, NOTUM, ABAT HDAC6 830/4885HDAC2 1034/4885HDAC8 700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.