Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28076473 | 0.89 | HTT (0.35) | HTTKMT2A | |
| SCHEMBL2250114 | 0.76 | HTT (0.52) | HTTKMT2AHRH4HRH3HRH1 | |
| SCHEMBL16680514 | 0.74 | SRD5A1 (0.50) | HTTKMT2A | |
| SCHEMBL28076438 | 0.72 | HTT (0.36) | HTTKMT2A | |
| SCHEMBL16679441 | 0.71 | BRD4 (0.52) | HTTKMT2A | |
| SCHEMBL16679416 | 0.71 | MAPK1 (0.45) | HTTKMT2AHRH4HRH3 | |
| SCHEMBL16690796 | 0.69 | MAPK1 (0.45) | HTTKMT2AMAP3K12 | |
| SCHEMBL28076436 | 0.68 | BMPR1B (0.33) | HTTKMT2AMAP3K12 | |
| SCHEMBL16679822 | 0.68 | MAPK1 (0.49) | — | |
| SCHEMBL29174308 | 0.68 | HTT (0.49) | HTTKMT2AHRH4HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658646-A | Aminoheteroaryl benzamides as kinase inhibitors | 诺华股份有限公司 | 2016-06-08 | — | — | CN | disclosed |