Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 3/20 | 0.49 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2810254 | 0.79 | ERN1 (0.56) | ERN1GRM5HAO1 | |
| SCHEMBL4978340 | 0.79 | ERN1 (0.49) | ERN1GRM5HAO1 | |
| SCHEMBL2809759 | 0.79 | ERN1 (0.49) | ERN1GRM5 | |
| SCHEMBL1809895 | 0.79 | FFAR1 (0.58) | GRM5NPC1RAB9A | |
| SCHEMBL30214468 | 0.79 | FFAR1 (0.58) | GRM5NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL19668206 | 0.77 | FFAR1 (0.57) | GRM5NPC1RAB9A | |
| SCHEMBL4980429 | 0.77 | GRM5 (0.68) | GRM5HAO1NPC1HCRTR1RAB9A | |
| SCHEMBL352291 | 0.77 | GRM5 (0.65) | GRM5 | |
| SCHEMBL25841112 | 0.76 | GRM5 (0.49) | ERN1GRM5NPC1HCRTR1RAB9A | |
| Hydrochloric Acid SCHEMBL3839867 | 0.76 | GRM5 (0.67) | GRM5HAO1NPC1HCRTR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2202221-A1 | ACETYLENE COMPOUND | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | ERN1 1196/4885GRM5 2797/4885HAO1 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.