Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.68 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3839867 | 0.98 | GRM5 (0.67) | GRM5HAO1NPC1HCRTR1RAB9A | |
| SCHEMBL704827 | 0.83 | GRM5 (0.68) | GRM5HAO1NPC1HCRTR1RAB9A | |
| SCHEMBL6132140 | 0.82 | GRM5 (0.66) | GRM5HAO1 | |
| SCHEMBL30707880 | 0.82 | GRM5 (0.66) | GRM5HAO1 | |
| SCHEMBL14573615 | 0.81 | GRM5 (1.00) | GRM5NPC1HCRTR1RAB9A | |
| SCHEMBL3959103 | 0.81 | GRM5 (1.00) | GRM5NPC1HCRTR1RAB9A | |
| SCHEMBL4267103 | 0.81 | CA12 (0.63) | GRM5HAO1 | |
| SCHEMBL3955131 | 0.80 | GRM5 (0.65) | GRM5 | |
| SCHEMBL30278437 | 0.80 | GRM5 (0.59) | GRM5HAO1 | |
| M-Mpep SCHEMBL29393403 | 0.79 | GRM5 (1.00) | GRM5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896448-A1 | AMINO-5-(6-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR ß-SECRETASE MODULATION | Wyeth (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007005404-A1 | AMINO-5-(6-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR ß-SECRETASE MODULATION | WYETH (US) | 2007-01-11 | — | — | WO | disclosed |