Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1825615 | 0.85 | — | — | |
| SCHEMBL28417773 | 0.79 | ALDH1A1 (0.30) | — | |
| Pyridine SCHEMBL2806204 | 0.76 | HDAC8 (0.37) | HDAC8TSHRNAPRTTDP1SLC6A2 | |
| Pyridine SCHEMBL1477186 | 0.76 | TSHR (0.39) | HDAC8TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL1477752 | 0.74 | TSHR (0.38) | HDAC8TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL1221198 | 0.72 | KMT2A (0.41) | HDAC8TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL1220102 | 0.72 | FFAR1 (0.37) | HDAC8TSHRNAPRTTDP1 | |
| Phenylacetylene SCHEMBL20602216 | 0.72 | HDAC8 (0.64) | HDAC8TSHRNAPRTTDP1SLC6A2 | |
| SCHEMBL28545188 | 0.68 | IDO1 (0.34) | — | |
| Pyridine SCHEMBL28828347 | 0.68 | TSHR (0.53) | HDAC8TSHRNAPRTTDP1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2202221-A1 | ACETYLENE COMPOUND | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | HDAC8 513/4885TSHR 3644/4885NAPRT 2041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.