Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | FGB | P02675 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290607 | 0.82 | IDO1 (0.47) | IDO1EP300KAT8ALDH1A1GAA | |
| SCHEMBL9382243 | 0.82 | IDO1 (0.47) | IDO1EP300KAT8ALDH1A1GAA | |
| SCHEMBL28468316 | 0.79 | SKP2 (0.44) | IDO1EP300KAT8ALDH1A1GAA | |
| SCHEMBL9317755 | 0.75 | CA1 (0.46) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL28207495 | 0.74 | IDO1 (0.45) | IDO1EP300KAT8ALDH1A1GAA | |
| SCHEMBL27354250 | 0.70 | ERN1 (0.45) | ALDH1A1TDP1TSHRMAPTRAB9A | |
| SCHEMBL5142101 | 0.69 | CA2 (0.41) | IDO1ALDH1A1GAACYP3A4TSHR | |
| SCHEMBL29181814 | 0.68 | IDO1 (0.44) | IDO1EP300KAT8ALDH1A1GAA | |
| SCHEMBL27945532 | 0.68 | IDO1 (0.44) | IDO1EP300KAT8ALDH1A1GAA | |
| SCHEMBL23515356 | 0.67 | IDO1 (0.51) | IDO1EP300KAT8MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103965147-B | Benzofuran derivatives | 武田药品工业株式会社 | 2016-08-24 | — | — | CN | disclosed |