Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3603579 | 0.77 | TSHR (0.31) | GAAHTTTSHRALDH1A1 | |
| SCHEMBL3599725 | 0.73 | TSHR (0.32) | HTTTSHRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL658198 | 0.73 | PTGS2 (0.31) | MAPTALDH1A1 | |
| SCHEMBL3600806 | 0.72 | NQO1 (0.33) | TDP2NSD2HSP90AA1PAX8HTT | |
| SCHEMBL659859 | 0.69 | TSHR (0.45) | GAAHTTTSHRMAPTALDH1A1 | |
| SCHEMBL659806 | 0.69 | ESR1 (0.42) | TDP2NSD2HSP90AA1PAX8ALDH1A1 | |
| SCHEMBL8388163 | 0.68 | CA1 (0.41) | GAAHTTTSHRMAPTALDH1A1 | |
| SCHEMBL6824008 | 0.68 | CA1 (0.42) | HSP90AA1GAAHTTTSHRMAPT | |
| SCHEMBL3597240 | 0.67 | PTGS1 (0.30) | — | |
| SCHEMBL18270608 | 0.67 | ESR1 (0.40) | GAATSHRMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103965147-B | Benzofuran derivatives | 武田药品工业株式会社 | 2016-08-24 | — | — | CN | disclosed |