Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PGR | P06401 | 4/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659388 | 0.77 | MAPT (0.36) | MAPTPGRALDH1A1HPGDCYP3A4 | |
| SCHEMBL659098 | 0.74 | KDM4E (0.31) | ALDH1A1HPGD | |
| SCHEMBL8719849 | 0.65 | ALDH1A1 (0.43) | MAPTPGRALDH1A1HPGDCYP3A4 | |
| SCHEMBL659806 | 0.65 | ESR1 (0.42) | ALDH1A1HPGDTDP1 | |
| SCHEMBL3600806 | 0.64 | NQO1 (0.33) | ALDH1A1HPGD | |
| SCHEMBL24625462 | 0.63 | ALDH1A1 (0.50) | MAPTPGRALDH1A1HPGDCYP3A4 | |
| SCHEMBL9052702 | 0.63 | MEN1 (0.50) | MAPTPGRALDH1A1HPGDCYP3A4 | |
| SCHEMBL10795565 | 0.62 | ALDH1A1 (0.52) | MAPTPGRALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL3603579 | 0.61 | TSHR (0.31) | ALDH1A1 | |
| SCHEMBL8712948 | 0.61 | MAPT (0.35) | MAPTALDH1A1HSD17B10CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103965147-B | Benzofuran derivatives | 武田药品工业株式会社 | 2016-08-24 | — | — | CN | disclosed |