Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | PYGM | P11217 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3740426 | 0.89 | LMNA (0.46) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL3740421 | 0.89 | LMNA (0.46) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL17948541 | 0.89 | LMNA (0.46) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL2338693 | 0.87 | LMNA (0.46) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL7194470 | 0.87 | LMNA (0.46) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL5697563 | 0.87 | LMNA (0.46) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL2583859 | 0.86 | LMNA (0.62) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL6297249 | 0.86 | LMNA (0.62) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL12230437 | 0.86 | LMNA (0.62) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL770113 | 0.86 | LMNA (0.62) | LMNAMTORALDH1A1THRBMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658658-A | Cytidine-5-carboxamide modified nucleotide compositions and methods related thereto | 私募蛋白质体公司 | 2016-06-08 | — | — | CN | disclosed |