Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5026580 | 0.83 | CYP2D6 (0.37) | TSHRHPGDPLA2G2CALDH1A1CYP3A4 | |
| SCHEMBL27408320 | 0.83 | CYP2D6 (0.37) | TSHRHPGDPLA2G2CALDH1A1CYP3A4 | |
| SCHEMBL21267787 | 0.83 | ALDH1A1 (0.48) | TSHRHPGDATMALDH1A1HCAR2 | |
| SCHEMBL11021687 | 0.79 | TSHR (0.49) | TSHRHPGDATMPLA2G2CALDH1A1 | |
| SCHEMBL3127236 | 0.79 | TSHR (0.49) | TSHRHPGDATMPLA2G2CALDH1A1 | |
| SCHEMBL27604138 | 0.78 | TDP1 (0.38) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| SCHEMBL27411781 | 0.78 | ALDH1A1 (0.39) | TSHRHPGDPLA2G2CALDH1A1CYP3A4 | |
| SCHEMBL28162464 | 0.77 | TSHR (0.47) | TSHRHPGDATMPLA2G2CALDH1A1 | |
| SCHEMBL3120813 | 0.77 | TSHR (0.47) | TSHRHPGDATMPLA2G2CALDH1A1 | |
| SCHEMBL8637991 | 0.76 | ALDH1A1 (0.58) | TSHRHPGDATMALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646369-A | Method for preparing rosuvastatin | 安徽美诺华药物化学有限公司 | 2016-06-08 | — | — | CN | claimed |
| CN-105646369-A | Method for preparing rosuvastatin | 安徽美诺华药物化学有限公司 | 2016-06-08 | — | — | CN | disclosed |