Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5828 | 0.91 | TDP1 (0.56) | TDP1KMT2AMEN1ATMGPR35 | |
| SCHEMBL12444133 | 0.91 | TDP1 (0.56) | TDP1KMT2AMEN1ATMGPR35 | |
| SCHEMBL29482305 | 0.91 | TDP1 (0.56) | TDP1KMT2AMEN1ATMGPR35 | |
| Hydrogen Sulfide SCHEMBL28228918 | 0.89 | TDP1 (0.54) | TDP1KMT2AMEN1ATMGPR35 | |
| SCHEMBL28001936 | 0.89 | TDP1 (0.54) | TDP1KMT2AMEN1ATMGPR35 | |
| Ethylene SCHEMBL28393415 | 0.87 | TDP1 (0.52) | TDP1KMT2AMEN1ATMGPR35 | |
| Nitrogen SCHEMBL11884111 | 0.87 | TDP1 (0.52) | TDP1KMT2AMEN1ATMGPR35 | |
| SCHEMBL28265640 | 0.86 | ALDH1A1 (0.50) | TDP1KMT2AMEN1ATMGPR35 | |
| Formic Acid SCHEMBL28219890 | 0.86 | TDP1 (0.47) | TDP1KMT2AMEN1ATMGPR35 | |
| SCHEMBL27561729 | 0.85 | NPC1 (0.52) | TDP1KMT2AMEN1ATMGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105837572-A | N-substituted phenylacrylamide derivative and its preparation method and purpose | 四川大学 | 2016-08-10 | — | — | CN | disclosed |