Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648603 | 0.94 | SLC6A4 (0.56) | SLC6A4DRD2BACE1KDM4ESLC6A2 | |
| SCHEMBL28228539 | 0.92 | BACE1 (0.54) | SLC6A4DRD2BACE1KDM4ESLC6A2 | |
| SCHEMBL3673985 | 0.92 | BACE1 (0.54) | SLC6A4DRD2BACE1KDM4ESLC6A2 | |
| Naphthalene SCHEMBL9359039 | 0.92 | BACE1 (0.54) | SLC6A4DRD2BACE1KDM4ESLC6A2 | |
| SCHEMBL3863146 | 0.91 | BACE1 (0.58) | SLC6A4DRD2BACE1ABL1HDAC4 | |
| SCHEMBL5400233 | 0.89 | SLC6A4 (0.56) | SLC6A4DRD2BACE1KDM4ESLC6A2 | |
| Methane SCHEMBL27919168 | 0.88 | BACE1 (0.51) | SLC6A4DRD2BACE1KDM4ESLC6A2 | |
| SCHEMBL9157501 | 0.87 | BACE1 (0.61) | SLC6A4DRD2BACE1ABL1HDAC4 | |
| SCHEMBL28543658 | 0.85 | BACE1 (0.59) | SLC6A4DRD2BACE1ABL1HDAC4 | |
| SCHEMBL5405317 | 0.85 | SLC6A4 (0.59) | SLC6A4DRD2KDM4ESLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105745213-A | Glycolurils having functional group and use thereof | 四国化成工业株式会社 | 2016-07-06 | — | — | CN | disclosed |