Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL10694365 | 0.94 | SLC6A4 (0.58) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL5400233 | 0.91 | SLC6A4 (0.56) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL4648603 | 0.91 | SLC6A4 (0.56) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL4458583 | 0.90 | SLC6A4 (0.55) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL28706053 | 0.90 | SLC6A4 (0.51) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| Naphthalene SCHEMBL9359039 | 0.89 | BACE1 (0.54) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL3673985 | 0.89 | BACE1 (0.54) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL28228539 | 0.89 | BACE1 (0.54) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL13737351 | 0.88 | SLC6A4 (0.54) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL13738724 | 0.88 | SLC6A4 (0.54) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118390073-A | Organic electrochemical synthesis method of cyclopropane compound | 南京林业大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-117088796-A | Method for synthesizing beta-trifluoromethylthioketone derivative by ring opening of cyclopropyl alcohol derivative | 天津师范大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-116730784-A | Synthesis method of malonic acid derivative | 华南理工大学 | 2023-09-12 | — | — | CN | disclosed |
| EP-3736265-A1 | (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS | Oryzon Genomics, S.A. (ES) | 2020-11-11 | — | — | EP | disclosed |
| US-7192684-B2 | Polymerizable silicon-containing compound, manufacturing method, polymer, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-20040067436-A1 | Polymerizable silicon-containing compound, manufacturing method, polymer, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
| US-4207241-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS AND ANTIPRURITIC AGENTS | SYNTEX CORPORATION (US) | 1980-06-10 | — | — | US | disclosed |
| US-4097674-A | ANTIINFLAMMATORY, ANTIPYRETIC, ANTIPRURITIC AGENTS, ANALGESICS | SYNTEX CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |
| US-4051233-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |
| US-4048330-A | Compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid esters used for treating inflammation, pain or pyrexia | SYNTEX CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4009197-A | 2-(6-Substituted-2'-naphthyl) acetic acid derivatives and the salts and esters thereof | SYNTEX CORPORATION (PM) | 1977-02-22 | — | — | US | disclosed |
| US-4001301-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, ANTI-PRURITIC | SYNTEX CORPORATION (PM) | 1977-01-04 | — | — | US | disclosed |
| US-3998966-A | Anti-inflammatory, analgesic, anti-pyretic and anti-pruritic 6-substituted 2-naphthyl acetic acid derivative-containing compositions and methods of use thereof | SYNTEX CORPORATION (PM) | 1976-12-21 | — | — | US | disclosed |
| US-3980699-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (PM) | 1976-09-14 | — | — | US | disclosed |
| US-3978124-A | ANALGESIC, ANTIPYRETIC | SYNTEX CORPORATION (PM) | 1976-08-31 | — | — | US | disclosed |
| US-3978116-A | ANALGESIC, ANTIPYRETIC | SYNTEX CORPORATION (PM) | 1976-08-31 | — | — | US | disclosed |