Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 14/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10071211 | 0.83 | CHEK1 (0.48) | CHEK1 | |
| SCHEMBL2810144 | 0.80 | NOTUM (0.43) | KCNQ3KCNQ2NOTUMCNR2 | |
| SCHEMBL185965 | 0.80 | CHEK1 (0.48) | CHEK1 | |
| SCHEMBL186155 | 0.78 | CHEK1 (0.47) | CHEK1 | |
| SCHEMBL185879 | 0.78 | CHEK1 (0.47) | CHEK1 | |
| SCHEMBL185440 | 0.75 | CHEK1 (0.51) | CHEK1 | |
| SCHEMBL880697 | 0.74 | MAPK1 (0.59) | KCNQ3KCNQ2PTPN1AR | |
| SCHEMBL13870414 | 0.73 | NOTUM (0.59) | NOTUM | |
| Hydrochloric Acid SCHEMBL853571 | 0.73 | MAPK1 (0.57) | KCNQ3KCNQ2PTPN1AR | |
| SCHEMBL24928920 | 0.72 | MAPK1 (0.44) | KCNQ3KCNQ2CHEK1PTPN1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131075-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-05-23 | — | — | US | disclosed |
| US-20100240669-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131075-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | KCNQ3 1094/4885KCNQ2 1474/4885NOTUM 2303/4885 |
| US-20100240669-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | KCNQ3 1094/4885KCNQ2 1474/4885NOTUM 2303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.