Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL4806171 | 0.88 | ALDH1A1 (0.43) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| Monoethanolamine SCHEMBL29182169 | 0.81 | ALDH1A1 (0.47) | ALDH1A1TSHR | |
| Ethylene Glycol SCHEMBL1595557 | 0.79 | TSHR (0.50) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| Ethylene Glycol SCHEMBL18049813 | 0.79 | TSHR (0.50) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| SCHEMBL157380 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| Monoethanolamine SCHEMBL1332111 | 0.78 | — | — | |
| Monoethanolamine SCHEMBL1331364 | 0.78 | — | — | |
| SCHEMBL8613971 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| SCHEMBL2508249 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| Monoethanolamine SCHEMBL14675689 | 0.78 | TSHR (1.00) | ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104619896-B | Acrylic fibre and manufacture method thereof and the fiber construct containing this fiber | 日本爱克兰工业株式会社 | 2016-08-24 | — | — | CN | disclosed |