Allylamine

Allylamine

SCHEMBL28077951

C=CCN.NC(=O)c1ccccc1C(N)=O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.54
ALDH1A1 P00352 5/20 0.50
HPGD P15428 4/20 0.50
TSHR P16473 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MAPT P10636 2/20 0.50
CYP3A4 P08684 1/20 0.47
METAP2 P50579 1/20 0.47
BCAT2 O15382 1/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
HTT P42858 1/20 0.43
PARP1 P09874 1/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.41
CTNNB1 P35222 1/20 0.41
SIRT1 Q96EB6 1/20 0.41
CYP1A2 P05177 1/20 0.41
IRAK4 Q9NWZ3 1/20 0.40
KEAP1 Q14145 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Allyl Alcohol SCHEMBL29155882 0.87 KDM4E (0.54) KDM4EALDH1A1HPGDTSHRHSD17B10
Phthalic Acid SCHEMBL29144166 0.83 ALDH1A1 (0.61) KDM4EALDH1A1HPGDTSHRHSD17B10
Phthalic Acid SCHEMBL28549489 0.83 ALDH1A1 (0.61) KDM4EALDH1A1HPGDTSHRHSD17B10
Ethylene SCHEMBL20567426 0.81 ALDH1A1 (0.64) KDM4EALDH1A1HPGDTSHRHSD17B10
Benzamide SCHEMBL11771049 0.81 CYP3A4 (0.67) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL39118 0.81 ALDH1A1 (0.70) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL27700719 0.81 ALDH1A1 (0.70) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL4967588 0.81 ALDH1A1 (0.70) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL5578215 0.80 KDM4E (0.49) KDM4EALDH1A1HPGDTSHRHSD17B10
Acrylic Acid SCHEMBL29610346 0.80 KDM4E (0.52) KDM4EALDH1A1HPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105777614-A Cyclamine alkylamide ferulate compound as well as preparation method and application thereof 南阳师范学院 2016-07-20 CN disclosed