Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL868319 | 0.91 | CRBN (0.39) | BLMCRBN | |
| Sulfuric Acid SCHEMBL292733 | 0.91 | BLM (0.42) | KDM4EBLMCYP2D6CYP2C19NPSR1 | |
| Phosphoric Acid SCHEMBL29143142 | 0.88 | CRBN (0.38) | BLMCRBN | |
| Sulfuric Acid SCHEMBL9576365 | 0.88 | BLM (0.40) | KDM4EBLMCYP2D6CYP2C19NPSR1 | |
| Sulfuric Acid SCHEMBL9449436 | 0.88 | BLM (0.40) | KDM4EBLMCYP2D6CYP2C19NPSR1 | |
| Phosphoric Acid SCHEMBL9418072 | 0.86 | CRBN (0.36) | BLMCRBN | |
| Phosphoric Acid SCHEMBL3682831 | 0.84 | CRBN (0.35) | CRBN | |
| Sulfuric Acid SCHEMBL9418046 | 0.84 | KDM4E (0.37) | KDM4EBLMCYP2D6CYP2C19NPSR1 | |
| Sulfamate SCHEMBL10951717 | 0.83 | TSHR (0.42) | KDM4EBLMCYP2D6CYP2C19NPSR1 | |
| Phosphoric Acid SCHEMBL18759116 | 0.80 | CYP1A2 (0.38) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349853-A | Fireproof coating for materials for wooden furniture | 桐乡市美意家具有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-105773765-A | Water-soluble loss-resisting flame retardant and method for preparing flame retardant wood with water-soluble loss-resisting flame retardant | 东北林业大学 | 2016-07-20 | — | — | CN | disclosed |