SCHEMBL28078043

SCHEMBL28078043

CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)CC1.CCOC(=O)c1cccc(N2CCN(C(=O)OC(C)(C)C)CC2)c1

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.58
MAPK1 P28482 1/20 0.52
CHRM4 P08173 2/20 0.50
HTR1A P08908 1/20 0.48
HTR7 P34969 1/20 0.48
LMNA P02545 1/20 0.47
GPR119 Q8TDV5 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL674604 0.90 GPR119 (0.56) MAPK1LMNAGPR119
SCHEMBL6707329 0.89 PRMT1 (0.67) PRMT1MAPK1HTR1AHTR7LMNA
Iodide SCHEMBL6706501 0.88 PRMT1 (0.66) PRMT1MAPK1HTR1AHTR7LMNA
SCHEMBL5569584 0.82 GPR119 (0.58) CHRM4HTR7LMNAGPR119
SCHEMBL4505636 0.82 GPR119 (0.56) MAPK1HTR1ALMNAGPR119
SCHEMBL6706537 0.82 TMEM97 (0.54) MAPK1HTR1ALMNA
SCHEMBL24317392 0.81 MAPK1 (0.57) PRMT1MAPK1LMNA
SCHEMBL28078045 0.81 NR1H2 (0.52) CHRM4GPR119
SCHEMBL31466702 0.80 TMEM97 (0.53) CHRM4HTR1AGPR119
SCHEMBL27468395 0.80 GPR119 (0.49) MAPK1LMNAGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN disclosed