Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292989 | 0.77 | TET2 (0.45) | TET2RECQLTSHRHSD17B10GAA | |
| SCHEMBL18039446 | 0.76 | TET2 (0.67) | TET2RECQLTSHRHSD17B10GAA | |
| SCHEMBL2185099 | 0.75 | EGLN1 (0.41) | HSD17B10KDM4EEGLN1ALDH1A1LMNA | |
| SCHEMBL10555722 | 0.75 | — | — | |
| SCHEMBL8470431 | 0.75 | TET2 (0.48) | TET2RECQLTSHRHSD17B10GAA | |
| SCHEMBL7826416 | 0.73 | — | — | |
| SCHEMBL17589193 | 0.73 | TET2 (0.61) | TET2RECQLTSHRHSD17B10GAA | |
| SCHEMBL28065431 | 0.71 | KDM4E (0.44) | TSHRGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL24741587 | 0.71 | TET2 (0.48) | TET2RECQLTSHRHSD17B10GAA | |
| SCHEMBL9632175 | 0.70 | TET2 (0.58) | TET2RECQLTSHRHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764904-A | Aza-pyridone compounds and uses thereof | 艾丽奥斯生物制药有限公司 | 2016-07-13 | — | — | CN | disclosed |