Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2247114 | 0.86 | TET2 (0.56) | TET2RECQLTSHRHSD17B10ALDH1A1 | |
| SCHEMBL9404556 | 0.80 | GAA (0.57) | TSHRHSD17B10ALDH1A1GAAKDM4E | |
| SCHEMBL7693144 | 0.80 | TET2 (0.40) | TET2RECQLTSHRHSD17B10ALDH1A1 | |
| SCHEMBL11184401 | 0.80 | ALDH1A1 (0.56) | TET2RECQLTSHRHSD17B10ALDH1A1 | |
| SCHEMBL523837 | 0.80 | CA2 (0.59) | TET2RECQLTSHRHSD17B10ALDH1A1 | |
| SCHEMBL8472411 | 0.79 | TET2 (0.39) | TET2RECQLTSHRHSD17B10ALDH1A1 | |
| SCHEMBL752297 | 0.78 | — | — | |
| SCHEMBL10555722 | 0.78 | — | — | |
| SCHEMBL3269747 | 0.78 | — | — | |
| SCHEMBL468803 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178299-A1 | PRODRUGS OF GANAXOLONE | MARINUS PHARMACEUTICALS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| CN-110746334-B | Method for preparing 3- (3-chloropropyl) -4-oxopyrrolidine-1-carboxylic ester | 上海朴颐化学科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-2621279-B1 | FUSED TETRACYCLE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME (US) | 2018-04-04 | — | — | EP | disclosed |
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |
| US-9740095-B2 | Green coloring composition for use in color filter, colored film, color filter, and solid-state imaging device | FUJIFILM CORPORATION (JP) | 2017-08-22 | — | — | US | disclosed |
| US-20160327860-A1 | GREEN COLORING COMPOSITION FOR USE IN COLOR FILTER, COLORED FILM, COLOR FILTER, AND SOLID-STATE IMAGING ELEMENT | FUJIFILM CORPORATION (JP) | 2016-11-10 | — | — | US | disclosed |
| WO-2010138790-A1 | ANTIVIRAL COMPOUNDS COMPOSED OF THREE ALIGNED ARYL MOIETIES TO TREAT DISEASES SUCH AS HEPATITIS C | SCHERING CORPORATION (US) | 2010-12-02 | — | — | WO | disclosed |
| US-20080299174-A1 | Bis-(Alpha-Amino)-Diol-Diester-Containing Poly (Ester Amide) and Poly (Ester Urethane) Compositions and Methods of Use | MEDIVAS, LLC | 2008-12-04 | — | — | US | disclosed |
| CN-1187329-C | Method for preparing 3-hydroxyindole derivative for indigo synthesis | KARLRO KAUS (AT) | 2005-02-02 | — | — | CN | disclosed |
| EP-0285270-B1 | A METHOD FOR PRODUCING 1-PROPARGYL-2,4-DIOXOIMIDAZOLIDINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-03 | — | — | EP | disclosed |
| US-4827020-A | Propargyl amide precursor to 1-propargyl-2,4-dioxoimidazolidine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-05-02 | — | — | US | disclosed |
| EP-0285270-A1 | A method for producing 1-propargyl-2,4-dioxoimidazolidine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-10-05 | — | — | EP | disclosed |
| US-4234744-A | Process for the production of aminoacid hydrochlorides/or diaminoacid dihydrochlorides | DEUTSCHE GOLD- UND SILBER SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080299174-A1 | Bis-(Alpha-Amino)-Diol-Diester-Containing Poly (Ester Amide) and Poly (Ester Urethane) Compositions and Methods of Use | APEH, DAO, DNPEP | TET2 3769/4885RECQL 4412/4885TSHR 3161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.