Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18250324 | 1.00 | TLR8 (0.57) | TLR8SMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL5824074 | 1.00 | TLR8 (0.57) | TLR8SMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL25067265 | 0.98 | TLR8 (0.59) | TLR8SMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL12424656 | 0.93 | ALDH1A1 (0.59) | TLR8SMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL29906127 | 0.87 | TLR8 (0.54) | TLR8SMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL29906137 | 0.87 | TLR8 (0.54) | TLR8SMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL27831297 | 0.87 | TLR8 (0.58) | TLR8SMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL29906144 | 0.87 | TLR8 (0.54) | TLR8SMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL27849754 | 0.87 | TLR8 (0.54) | TLR8SMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL27925787 | 0.87 | TLR8 (0.54) | TLR8SMN1; SMN2ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777642-A | N1 position-substituted imidazole compound and alkaline anion exchange membrane, and preparation methods thereof | 中国科学院大连化学物理研究所 | 2016-07-20 | — | — | CN | disclosed |