Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | POLA1 | P09884 | 1/20 | 0.52 |
| ▸ | PNP | P00491 | 2/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.45 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pterine SCHEMBL27777837 | 0.94 | POLB (0.47) | POLGPOLBPOLA1PNPAKR1B1 | |
| Pterine SCHEMBL2411220 | 0.90 | PNP (0.51) | POLGPOLBPOLA1PNPAKR1B1 | |
| Pterine SCHEMBL4879287 | 0.88 | AKR1B1 (0.51) | PNPAKR1B1NOS1HSD17B10 | |
| Pterine SCHEMBL23295082 | 0.83 | AKR1B1 (0.55) | PNPAKR1B1NOS1HSD17B10 | |
| Pterine SCHEMBL9444227 | 0.83 | AKR1B1 (0.59) | PNPAKR1B1NOS1HSD17B10 | |
| Pterine SCHEMBL29364680 | 0.83 | AKR1B1 (0.54) | PNPAKR1B1NOS1HSD17B10 | |
| Pterine SCHEMBL64320 | 0.83 | AKR1B1 (0.54) | PNPAKR1B1NOS1HSD17B10 | |
| Pterine SCHEMBL906054 | 0.82 | AKR1B1 (0.53) | PNPAKR1B1NOS1HSD17B10 | |
| Pterine SCHEMBL31296557 | 0.82 | AKR1B1 (0.53) | PNPAKR1B1NOS1HSD17B10 | |
| Pterine SCHEMBL5703596 | 0.82 | AKR1B1 (0.53) | PNPAKR1B1NOS1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105861339-B | Recombination Mortierella alpina, its construction method and the application of one plant of overexpression GTP cyclohydrolase gene | 江南大学 | 2019-10-18 | — | — | CN | disclosed |
| CN-105861339-A | Recombination mortierella alpine of overexpression GTP ring type hydrolytic enzyme gene and construction method and application of recombination mortierella alpine | 江南大学 | 2016-08-17 | — | — | CN | disclosed |