Pterine

Pterine

SCHEMBL29364680

Nc1nc2nccnc2c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.54
THRB P10828 2/20 0.53
MITF O75030 1/20 0.53
TP53 P04637 1/20 0.53
ALOX15 P16050 1/20 0.53
HBB P68871 1/20 0.53
HIF1A Q16665 1/20 0.53
NOS1 P29475 8/20 0.51
PNP P00491 2/20 0.50
HSD17B10 Q99714 3/20 0.49
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 2/20 0.49
LMNA P02545 1/20 0.49
GLA P06280 1/20 0.49
PMP22 Q01453 1/20 0.49
MEN1 O00255 1/20 0.49
MAPT P10636 1/20 0.49
HPGD P15428 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pterine SCHEMBL64320 1.00 AKR1B1 (0.54) AKR1B1THRBMITFTP53ALOX15
Pterine SCHEMBL27339749 0.98 AKR1B1 (0.53) AKR1B1THRBMITFTP53ALOX15
Pterine SCHEMBL30474634 0.98 AKR1B1 (0.53) AKR1B1THRBMITFTP53ALOX15
Pterine SCHEMBL27566961 0.98 AKR1B1 (0.53) AKR1B1THRBMITFTP53ALOX15
Pterine SCHEMBL31296557 0.98 AKR1B1 (0.53) AKR1B1THRBMITFTP53ALOX15
Pterine SCHEMBL31190985 0.98 AKR1B1 (0.53) AKR1B1THRBMITFTP53ALOX15
Pterine SCHEMBL452642 0.98 AKR1B1 (0.53) AKR1B1THRBMITFTP53ALOX15
Pterine SCHEMBL5703596 0.98 AKR1B1 (0.53) AKR1B1THRBMITFTP53ALOX15
Pterine SCHEMBL906054 0.98 AKR1B1 (0.53) AKR1B1THRBMITFTP53ALOX15
Pterine SCHEMBL28042087 0.98 AKR1B1 (0.53) AKR1B1THRBMITFTP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025015936-A1 PREPARATION METHOD FOR CURCUMIN-LOADED RECOMBINANT COLLAGEN HYDROGEL AND USE OF CURCUMIN-LOADED RECOMBINANT COLLAGEN HYDROGEL IN TREATMENT OF INTRAUTERINE ADHESION 江苏创健医疗科技股份有限公司 2025-01-23 WO claimed
CN-221618339-U Uterine cavity adhesion preventing device 江苏德威兰医疗器械股份有限公司 2024-08-30 CN claimed
WO-2024125344-A1 PREPARATION METHOD FOR TEMPERATURE-SENSITIVE HYDROGEL AND USE THEREOF 湖南创健医疗器械有限公司 2024-06-20 WO claimed
CN-117185983-A Bisoxindole compound, preparation method thereof and application thereof in preparation of antibacterial agent 浙江工业大学 2023-12-08 CN claimed
CN-116535419-A Amino compound, organic electroluminescent element and organic electroluminescent device 北京八亿时空液晶科技股份有限公司 2023-08-04 CN claimed
CN-219109526-U Probe for intrauterine ultrasound 胡新阳 2023-06-02 CN claimed
CN-116158822-A Endometrium uterine curettage device for gynaecology 商杰 2023-05-26 CN claimed
CN-219001692-U Balloon device containing estrogen for preventing uterine cavity adhesion 深圳市罗湖区妇幼保健院 2023-05-12 CN claimed
US-20260144238-A1 SKIN TISSUE THE UNIVERSITY OF TOKYO (JP) 2026-05-28 US disclosed
US-12630593-B2 Method of killing leukemia cells by administration of recombinant'Y3 proteins UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2026-05-19 US disclosed
US-20260124473-A1 HISTOTRIPSY USING VERY SHORT ULTRASOUND PULSES UNIV MICHIGAN REGENTS (US) 2026-05-07 US disclosed
US-20260102239-A1 METHODS OF ESTABLISHING STEM CELL CULTURES FROM LOW-QUALITY EMBRYOS TO INCREASE THE RATE OF GENETIC PROGRESS INGURAN, LLC (US) 2026-04-16 US disclosed
EP-3464342-B1 MUTANT LIGHT-INDUCIBLE ION CHANNEL OF CHRIMSON MAX PLANCK GESELLSCHAFT (DE) 2026-03-18 EP disclosed
US-12533360-B2 Inhibition of BRD proteins suppresses the phenotype of uterine fibroids THE UNIVERSITY OF CHICAGO (US) 2026-01-27 US disclosed
CN-114596765-A DNA double helix teaching aid 中国地质科学院地质力学研究所 2022-06-07 CN disclosed
CN-114596765-A DNA double helix teaching aid 中国地质科学院地质力学研究所 2022-06-07 CN disclosed
US-11337944-B2 Method of treating colorectal cancers using a PKC inhibitor UNIVERSITY OF SOUTH FLORIDA (US) 2022-05-24 US disclosed
CN-114469874-A Traditional Chinese medicine formula granules for treating gout and preparation method thereof 深圳朝康医药有限公司 2022-05-13 CN disclosed
CN-114317671-A Intestinal bacteria and fecal metabolites capable of being used as biomarkers of type 1diabetes and application thereof 复旦大学附属儿科医院 2022-04-12 CN disclosed
CN-110023741-B Biological particle counting system and biological particle counting method 理音株式会社 2022-01-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630593-B2 Method of killing leukemia cells by administration of recombinant'Y3 proteins L3MBTL3, CHI3L1, BCL3 AKR1B1 4128/4885THRB 1852/4885MITF 4339/4885
US-20260102239-A1 METHODS OF ESTABLISHING STEM CELL CULTURES FROM LOW-QUALITY EMBRYOS TO INCREASE THE RATE OF GENETIC PROGRESS ALPG, PGF, ALPP AKR1B1 4110/4885THRB 4383/4885MITF 1174/4885
US-20260124473-A1 HISTOTRIPSY USING VERY SHORT ULTRASOUND PULSES PIEZO1, SON, BUB3 AKR1B1 4808/4885THRB 1360/4885MITF 1552/4885
US-20260144238-A1 SKIN TISSUE KRT18, EPCAM, CUTA AKR1B1 4115/4885THRB 4097/4885MITF 196/4885
US-12533360-B2 Inhibition of BRD proteins suppresses the phenotype of uterine fibroids BRD2, BRDT, BRD1 AKR1B1 4450/4885THRB 1889/4885MITF 2736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.