Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | CD81 | P60033 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290896 | 0.95 | TBXAS1 (0.35) | EP300TBXAS1CD81APEX1LMNA | |
| SCHEMBL111604 | 0.95 | TBXAS1 (0.35) | EP300TBXAS1CD81APEX1LMNA | |
| Hydrogen Sulfide SCHEMBL379592 | 0.93 | TBXAS1 (0.34) | EP300TBXAS1CD81APEX1LMNA | |
| SCHEMBL1425200 | 0.93 | TBXAS1 (0.34) | EP300TBXAS1CD81APEX1 | |
| SCHEMBL1425197 | 0.93 | TBXAS1 (0.34) | EP300TBXAS1CD81APEX1 | |
| Methacrylic Acid SCHEMBL8054981 | 0.89 | TBXAS1 (0.32) | TBXAS1CD81APEX1 | |
| Methacrylic Acid SCHEMBL8054974 | 0.89 | TBXAS1 (0.32) | TBXAS1CD81APEX1 | |
| Hydrogen Sulfide SCHEMBL28537418 | 0.88 | TBXAS1 (0.36) | EP300TBXAS1CD81APEX1LMNA | |
| SCHEMBL23413225 | 0.84 | APEX1 (0.35) | TBXAS1CD81APEX1 | |
| SCHEMBL1218931 | 0.84 | APEX1 (0.35) | TBXAS1CD81APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109609462-A | A kind of high throughput three-dimensional cell bead culture and antibiotics susceptibility test method in situ | 北京航空航天大学 | 2019-04-12 | — | — | CN | disclosed |
| CN-105861309-B | A kind of super-hydrophobic micro-pit array chip and preparation method and application | 清华大学 | 2018-05-11 | — | — | CN | disclosed |
| CN-105861309-A | Super-hydrophobic micro-pit array chip and preparation method and application thereof | 清华大学 | 2016-08-17 | — | — | CN | disclosed |