Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SNCA | P37840 | 2/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14041609 | 0.85 | HTR6 (0.33) | SNCAHTR6 | |
| Hydromethylthionine SCHEMBL109756 | 0.82 | SNCA (0.50) | MAPTSNCANOX1MEN1MAPK1 | |
| Hydromethylthionine SCHEMBL12592446 | 0.82 | SNCA (0.50) | MAPTSNCANOX1MEN1MAPK1 | |
| Hydromethylthionine SCHEMBL29356148 | 0.82 | SNCA (0.50) | MAPTSNCANOX1MEN1MAPK1 | |
| Hydromethylthionine SCHEMBL23683393 | 0.80 | SNCA (0.48) | MAPTSNCANOX1MEN1MAPK1 | |
| Hydromethylthionine SCHEMBL1577040 | 0.80 | SNCA (0.48) | MAPTSNCANOX1MEN1MAPK1 | |
| Hydromethylthionine SCHEMBL31159649 | 0.80 | SNCA (0.48) | MAPTSNCANOX1MEN1MAPK1 | |
| Hydromethylthionine SCHEMBL25194477 | 0.80 | SNCA (0.48) | MAPTSNCANOX1MEN1MAPK1 | |
| Hydromethylthionine SCHEMBL12470963 | 0.80 | SNCA (0.48) | MAPTSNCANOX1MEN1MAPK1 | |
| Hydromethylthionine SCHEMBL31159642 | 0.80 | SNCA (0.48) | MAPTSNCANOX1MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683171-A | Chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (MTC) | 维斯塔实验室有限公司 | 2016-06-15 | — | — | CN | disclosed |