Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29737981 | 0.93 | — | — | |
| SCHEMBL411439 | 0.93 | — | — | |
| SCHEMBL20969967 | 0.90 | KEAP1 (0.34) | KEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL16992865 | 0.73 | — | — | |
| SCHEMBL30411719 | 0.73 | — | — | |
| SCHEMBL27799893 | 0.73 | TSHR (0.40) | — | |
| SCHEMBL22824181 | 0.72 | — | — | |
| SCHEMBL28119509 | 0.69 | TSHR (0.48) | NFE2L2 | |
| SCHEMBL22978713 | 0.68 | — | — | |
| SCHEMBL20969966 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254514-B | 4 ((substituted-phenyl) difluoromethyl) phenoxy carboxylic acid derivatives and its production and use | 浙江海正药业股份有限公司 | 2017-06-27 | — | — | CN | claimed |
| CN-105777585-A | Method for synthesizing aliphatic or alicyclic diamido formate | 安徽华荣高科新材料股份有限公司 | 2016-07-20 | — | — | CN | claimed |
| CN-105237483-B | A kind of symmetric form pyrimidine radicals salt compounded of iodine and preparation method thereof | 东华大学 | 2018-04-20 | — | — | CN | disclosed |
| CN-106795123-A | Fluorocytosine and fluorocytosine derivatives | 杜伦大学 | 2017-05-31 | — | — | CN | disclosed |
| CN-105777585-A | Method for synthesizing aliphatic or alicyclic diamido formate | 安徽华荣高科新材料股份有限公司 | 2016-07-20 | — | — | CN | disclosed |