Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28079025 | 0.71 | ALDH1A1 (0.49) | TOP1ALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL2053519 | 0.69 | KDM4E (0.52) | TOP1ALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL1075533 | 0.69 | PDE10A (0.50) | ALDH1A1HPGDHSD17B10NPC1RAB9A | |
| SCHEMBL22733867 | 0.69 | ALDH1A1 (0.49) | TOP1ALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL5473233 | 0.65 | MEN1 (0.33) | ALDH1A1HPGDHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL521943 | 0.65 | ALDH1A1 (0.62) | TOP1ALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL28741694 | 0.62 | ALDH1A1 (0.51) | TOP1ALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL28078897 | 0.62 | ALDH1A1 (0.51) | TOP1ALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL27331118 | 0.61 | ALDH1A1 (0.50) | TOP1ALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL5469628 | 0.61 | MEN1 (0.33) | ALDH1A1HPGDHSD17B10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793421-A | Resistant mutant 90 kDa heat shock protein | 大鹏药品工业株式会社 | 2016-07-20 | — | — | CN | disclosed |