Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.40 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28427127 | 0.78 | MAPT (0.44) | MAPTMAOBRECQLPLIN1LMNA | |
| SCHEMBL11872634 | 0.73 | MAPT (0.40) | MAPTMAOBRECQLPLIN1LMNA | |
| SCHEMBL1076588 | 0.71 | MAPT (0.41) | MAPTMAOBRECQLPLIN1LMNA | |
| SCHEMBL28124739 | 0.70 | MAPT (0.42) | MAPTMAOBCYP1B1RAB9ACYP3A4 | |
| SCHEMBL21807724 | 0.70 | MAPT (0.39) | MAPTMAOBRECQLPLIN1LMNA | |
| SCHEMBL21807722 | 0.70 | MAPT (0.39) | MAPTMAOBRECQLPLIN1LMNA | |
| SCHEMBL1938587 | 0.69 | NPC1 (0.41) | MAPTMAOBRECQLLMNACYP1B1 | |
| SCHEMBL11406085 | 0.68 | MAPT (0.43) | MAPTMAOBRECQLPLIN1LMNA | |
| SCHEMBL31471657 | 0.68 | MAPT (0.43) | MAPTMAOBRECQLPLIN1LMNA | |
| SCHEMBL1992490 | 0.68 | MAPT (0.43) | MAPTMAOBRECQLPLIN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905278-B | A method of 5 kinds of separation preparation has antiinflammatory active compound from falcate crazyweed herb | 中国科学院西北高原生物研究所 | 2019-08-23 | — | — | CN | claimed |
| CN-105884736-B | A kind of method that separation prepares 5 kinds of flavone compounds from falcate crazyweed herb | 中国科学院西北高原生物研究所 | 2018-04-06 | — | — | CN | claimed |
| CN-106905278-A | A kind of separation from falcate crazyweed herb prepares 5 kinds of methods with antiinflammatory active compound | 中国科学院西北高原生物研究所 | 2017-06-30 | — | — | CN | claimed |
| CN-105884736-A | Method for separating and preparing 5 flavonoid compounds from Oxytropis falcate Bunge | 中国科学院西北高原生物研究所 | 2016-08-24 | — | — | CN | claimed |
| CN-105796548-A | Flavonoid drug composition and preparation method and application | 中国科学院西北高原生物研究所 | 2016-07-27 | — | — | CN | claimed |
| CN-105796548-B | Flavonoid pharmaceutical composition, preparation method and application | 中国科学院西北高原生物研究所 | 2020-04-24 | — | — | CN | disclosed |
| CN-106905278-B | A method of 5 kinds of separation preparation has antiinflammatory active compound from falcate crazyweed herb | 中国科学院西北高原生物研究所 | 2019-08-23 | — | — | CN | disclosed |
| CN-106905278-B | A method of 5 kinds of separation preparation has antiinflammatory active compound from falcate crazyweed herb | 中国科学院西北高原生物研究所 | 2019-08-23 | — | — | CN | disclosed |
| CN-109912398-A | A method of extracting and developing purifies 5 kinds of chalcone from Northeastern crowberry | 聊城大学 | 2019-06-21 | — | — | CN | disclosed |
| CN-109912398-A | A method of extracting and developing purifies 5 kinds of chalcone from Northeastern crowberry | 聊城大学 | 2019-06-21 | — | — | CN | disclosed |
| CN-105884736-B | A kind of method that separation prepares 5 kinds of flavone compounds from falcate crazyweed herb | 中国科学院西北高原生物研究所 | 2018-04-06 | — | — | CN | disclosed |
| CN-106905278-A | A kind of separation from falcate crazyweed herb prepares 5 kinds of methods with antiinflammatory active compound | 中国科学院西北高原生物研究所 | 2017-06-30 | — | — | CN | disclosed |
| CN-106727881-A | A kind of extracting method with anti-inflammatory activity general flavone from falcate crazyweed herb | 中国科学院西北高原生物研究所 | 2017-05-31 | — | — | CN | disclosed |
| CN-105884736-A | Method for separating and preparing 5 flavonoid compounds from Oxytropis falcate Bunge | 中国科学院西北高原生物研究所 | 2016-08-24 | — | — | CN | disclosed |
| CN-105796548-A | Flavonoid drug composition and preparation method and application | 中国科学院西北高原生物研究所 | 2016-07-27 | — | — | CN | disclosed |