Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922740 | 0.85 | ADRB2 (0.71) | ADRB2ADRB1KMT2AMEN1L3MBTL1 | |
| SCHEMBL30416351 | 0.84 | ADRB2 (0.65) | ADRB2ADRB1KMT2AMEN1L3MBTL1 | |
| SCHEMBL1496566 | 0.84 | ADRB2 (0.65) | ADRB2ADRB1KMT2AMEN1L3MBTL1 | |
| SCHEMBL2477290 | 0.82 | MAPK1 (0.68) | L3MBTL1MAPTTSHRMAPK1HIF1A | |
| Hydrochloric Acid SCHEMBL9142587 | 0.82 | ADRB2 (0.63) | ADRB2ADRB1KMT2AMEN1L3MBTL1 | |
| SCHEMBL10457357 | 0.82 | ADRB2 (0.63) | ADRB2ADRB1KMT2AMEN1L3MBTL1 | |
| SCHEMBL1496789 | 0.81 | TSHR (0.71) | ADRB2ADRB1KMT2AMEN1L3MBTL1 | |
| SCHEMBL1496742 | 0.81 | ADRB2 (0.66) | ADRB2ADRB1KMT2AMEN1L3MBTL1 | |
| SCHEMBL14896741 | 0.81 | TSHR (0.71) | ADRB2ADRB1KMT2AMEN1L3MBTL1 | |
| SCHEMBL16002431 | 0.81 | TSHR (0.71) | ADRB2ADRB1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658238-A | Therapeutic agents for use in the prophylaxis and/or treatment of hyperkinetic movement disorders | 索姆创新生物技术公司 | 2016-06-08 | — | — | CN | disclosed |