Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | RPA1 | P27694 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16517038 | 0.81 | MAP3K14 (0.44) | MAP3K14RPA1ELANEPOLB | |
| SCHEMBL16517651 | 0.77 | ELANE (0.53) | MAP3K14RPA1ELANE | |
| SCHEMBL28079398 | 0.72 | KCNH2 (0.39) | — | |
| SCHEMBL16517695 | 0.70 | ALDH1A1 (0.40) | MAP3K14RPA1ELANEPOLB | |
| SCHEMBL2648767 | 0.69 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL16547223 | 0.69 | ELANE (0.53) | RPA1ELANE | |
| SCHEMBL16517295 | 0.67 | ELANE (0.51) | RPA1ELANE | |
| SCHEMBL16516961 | 0.67 | ELANE (0.51) | MAP3K14RPA1ELANE | |
| SCHEMBL16517373 | 0.66 | MAPT (0.41) | RPA1ELANEKMT2A | |
| SCHEMBL16516318 | 0.66 | MAP3K14 (0.49) | MAP3K14MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658640-A | Alkynyl alcohols and methods of use | 豪夫迈·罗氏有限公司 | 2016-06-08 | — | — | CN | disclosed |