Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | BRS3 | P32247 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30591339 | 0.85 | PTGS2 (0.54) | PTGS2NAPRTEGFRNLRP3KEAP1 | |
| SCHEMBL26282749 | 0.85 | PTGS2 (0.54) | PTGS2NAPRTEGFRNLRP3KEAP1 | |
| SCHEMBL5394506 | 0.82 | CA1 (0.57) | PTGS2CA12CA1CA7CA14 | |
| SCHEMBL12880366 | 0.81 | PTGS2 (0.52) | RAB9APTGS2NAPRTEGFRNLRP3 | |
| SCHEMBL6390027 | 0.80 | HIF1A (0.50) | PTGS2NAPRTEGFRNLRP3KEAP1 | |
| SCHEMBL2221393 | 0.79 | HDAC8 (0.50) | RAB9ANAMPT | |
| SCHEMBL2221395 | 0.79 | HDAC8 (0.50) | RAB9ANAMPT | |
| SCHEMBL15625451 | 0.79 | PTGS2 (0.56) | PTGS2NAPRTEGFRNLRP3KEAP1 | |
| SCHEMBL7088891 | 0.78 | NAMPT (0.55) | RAB9ANAMPTCA12CA1CA7 | |
| SCHEMBL9062856 | 0.77 | ITGAV (0.59) | RAB9ANAMPTSLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130855-B | Succinylated hydroxy amine derivatives and application thereof | 约翰斯霍普金斯大学 | 2018-05-25 | — | — | CN | disclosed |
| CN-105919987-A | N-acyloxysulfonamide And N-hydroxy-n-acylsulfonamide Derivatives And Use Thereof | 约翰斯霍普金斯大学 | 2016-09-07 | — | — | CN | disclosed |
| CN-102753520-B | N-acyloxysulfonamide and N-hydroxy-N-acylsulfonamide derivatives | 约翰斯霍普金斯大学 | 2016-06-08 | — | — | CN | disclosed |